South Carolina Nightclubs

Looking for the Top Nightclubs in South Carolina?

Check out our listing of the hottest clubs in South Carolina, read reviews, view upcoming events and more.

Toucan Reef image

Toucan Reef

360 Concord St, Charleston, South Carolina United States

This event is being put together by 2 of Charleston's earliest dj promotional groups in underground dance music, Groovers Afterhours and Fuse. Groovers Afterhours was a collaboration that started in 1994. At first, they hosted one-off events, then developed into a venue on Calhoun St. Fuse came around about 1998 and continues to host several [more]

Rooftop Bar at Poseidon

38 Shelter Cove Ln, Hilton Head Island, South Carolina United States

*21 and over only please Have fun, but please adhere to the following dress code: Resort casual daily; NO baggy, saggy, ripped clothing or sleeveless tshirts Friday and Saturday - Dress to impress after 7pm: NO skull caps, bandannas, athletic wear, or t-shirts. [more]

City Bar

5 Faber St., Charleston, South Carolina United States


Charleston's premiere destination for the last 5 years, no other nightclub in the city hostes bigger or hotter crowds than CITY BAR. Internationally recognized & packed each night w/ a different vibe and feel. A club that you'd expect to find in cities like Miami, New York or Vegas and filled w/ the most attractive, friendly and uninhibited [more]


3052 Howard St, Spartanburg, South Carolina United States

Rock N Roll club that has hosted Incubus , Hank III , White Chapel , Lamb Of God , Bullet For My Valentine , Slayer , Kid Rock ,Ted Nugent , Megadeth , ICP just to name a few . The new location is 650 cap . Open to any genre and everyone is welcome . Cash bar , cheapest drinks and alot of history . Alot of famous bands started out playing [more]

Lust Greenville

216 Transit Drive Greenville, Greenville, South Carolina United States

Lust Greenville [more]